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Most Common Birth Defects

According to The Centers for Disease Control and Prevention, birth defects affect one in every 33 babies born in the U.S. each year. That means a baby is born with a birth defect every 4.5 minutes. Birth defects are the leading cause of infant deaths, accounting for 20% of all infant deaths. Here is a list of some of the most common major birth affects:

Central Nervous System Defects

    • Anencephaly
    • Spina bifida without anencephaly
    • Encephalocele
    • Evaluation for Zika virus related abnormalities
    • Dandy Walker Defect
    • Fetal brain malformations

Eye Defects

  • Anophthalmia/microphthalmia

Heart/Cardiovascular Defects

  • Common arterial trunk (Truncus arteriosus)
  • Transposition of great arteries
  • Tetralogy of Fallot
  • Atrioventricular septal defect
  • Hypoplastic left heart syndrome
  • Ventricular septal defects
  • Atriial isomerism disorders
  • Fetal arrhythmias

Facial Defects

  • Cleft palate without cleft lip
  • Cleft lip with or without cleft palate

Gastrointestinal Defects

  • Esophageal atresia/tracheoesophageal fistula
  • Rectal and large intestinal atresia/stenosis
  • Duodenal atresia
  • Gastroschisis
  • Omphalocele
  • Diaphragmatic Hernia

Musculoskeletal Defects

  • Reduction deformity, upper limbs
  • Reduction deformity, lower limbs
  • Club foot
  • Spinal abnormalities
  • Skeletal dysplasias

Chromosomal Anomalies

  • Trisomy 13
  • Trisomy 18
  • Trisomy 21 (Down syndrome)
  • Turner Syndrome
  • DiGeorge Syndrome (22q Deletion)

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